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Am J Case Rep ; 21: e922000, 2020 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-32291384

RESUMO

BACKGROUND Consumption coagulopathy post envenomation is one the most common complications after a snakebite. It occurs secondary to activation of a coagulation cascade by snake venom and could be followed by a syndrome consistent with thrombotic microangiopathy. The efficacy of plasma exchange for the treatment of thrombotic microangiopathy post envenomation is a matter of debate. CASE REPORT We reported the case of a 50-year-old male who had Arabian saw-scaled viper envenomation. He developed venom induced coagulopathy that improved within 24 hours of antivenom therapy. He subsequently developed micro-angiopathic hemolytic anemia, thrombocytopenia, and renal failure that was consistent with thrombotic microangiopathy. The patient was treated by plasma exchange and hemodialysis. He made a full recovery and was discharged after 4 weeks. CONCLUSIONS This case report supports plasmapheresis as an option for management of a patient who develops thrombotic microangiopathy secondary to snake bite, especially those who do not improve with antivenom and supportive therapy.


Assuntos
Mordeduras de Serpentes/complicações , Microangiopatias Trombóticas/diagnóstico , Animais , Coagulação Intravascular Disseminada , Humanos , Masculino , Pessoa de Meia-Idade , Troca Plasmática , Diálise Renal , Microangiopatias Trombóticas/terapia , Venenos de Víboras/intoxicação , Viperidae
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